Artificial fragrance free
Dye free
Paraben free
Sulfate free
Phthalate free
Animal cruelty free
IntelliRET™ 1.0+
IntelliRET™ 1.0+
Our highest-strength retinol serum, powered by intelligent time-release technology and a bio-inspired botanical complex that boosts the effects of retinol, targeting deep lines, loss of firmness, and stubborn discoloration while supporting optimal skin tolerance.
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Description
Our highest-strength retinol serum, powered by intelligent time-release technology and a bio-inspired botanical complex that boosts the effects of retinol, targeting deep lines, loss of firmness, and stubborn discoloration while supporting optimal skin tolerance.
IntelliRET™ 1.0+ is the most advanced step in the IntelliRET™ system, created for experienced retinol users seeking maximum corrective performance. With 1.0% retinol, it targets deep fine lines and wrinkles, loss of firmness, stubborn discoloration, blemishes, and uneven texture. The bio-inspired botanical complex enhances the efficacy of retinol and improves skin tolerance, making this level of performance achievable without the barrier disruption traditionally associated with high-strength retinol.
At the core of its delivery system is cutting-edge microencapsulated retinol, which allows for a gradual, timed-release overnight, maximizing efficacy while minimizing irritation. The formula is further enriched with soothing and hydrating ingredients like niacinamide and sodium hyaluronate for visible results, delivered in comfort.
Recommended once your skin is comfortable with consistent use of IntelliRET™ 0.5+. Use as directed by your skincare professional.
IntelliRET™ 1.0+ is part of AlumierMD’s Core 4 Essentials, designed to target visible signs of aging driven by Oxidative Aging™ and support long-term skin resilience as part of a complete daily defense approach.
Contains Vitamin A. Consider your daily intake before use.
Key Benefits
- Maximum retinol performance that targets the appearance of deep fine lines and wrinkles, significant loss of firmness, stubborn discoloration, and blemish-prone skin.
- Bio-inspired botanical booster (Chlorella vulgaris) amplifies visible results and supports a more balanced skin response at maximum retinol concentration.
- Microencapsulated retinol for controlled delivery, maintaining maximum efficacy while reducing the barrier disruption that typically limits high-strength retinol use.
- Niacinamide provides essential barrier reinforcement at this concentration to support ongoing skin comfort and tolerance.
- MATRIXYL® Synthe'6® visibly supports skin structure and helps improve the appearance of loss of firmness alongside retinol's smoothing effects.
- Targeted calming complex helps manage the visible signs of skin stress at higher retinol concentrations for more comfortable sustained use.
- The final and highest step in the IntelliRET™ progressive strength pathway, for experienced retinol users.
- Precision-dose needlenose tube for precise, hygienic application. Professional guidance required.
Directions
Apply a pea sized amount to face after cleansing at night, as directed by your skincare professional. Follow with your favorite AlumierMD moisturizer. For use only once your skin is comfortable with nightly use of IntelliRET™ 0.5+. Begin using once or twice a week and increase frequency only as directed by your skincare professional. Not suitable for those new to retinol, or for rosacea, highly reactive, or compromised skin.
Cautions: For external use only. Avoid contact with eyes, eyelids, and mucous membranes. Keep out of reach of children. Use only as directed. If irritation occurs or persists, discontinue use and consult a physician. Do not use if you are pregnant, lactating or planning to become pregnant.
Contains Vitamin A. Consider your daily intake before use.
Sunburn Alert: This product contains retinol that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.
Ingredients
Microencapsulated Retinol (1%): A vitamin A derivative and antioxidant that reduces the look of fine lines and wrinkles and improves texture and tone by strengthening skin, and increasing skin turnover. Retinol exfoliates to help decongest pores and reduce the look of discoloration, making it suitable for blemish-prone skin. Encapsulated retinol allows for a slow release into the skin overnight minimizing side effects, so you can enjoy all the benefits of retinol with little to no irritation.
Niacinamide (vitamin B3): Along with keeping in moisture and boosting hydration, it also increases tolerance to topical retinoids.
MATRIXYL® Synthe'6®: Derived from a peptide naturally found in collagen and laminins, this visibly supports skin structure and targets the look of stubborn wrinkles and skin firmness.
Tetrapeptide-14, Green Tea Extract, Boswellia Serrata Gum: A peptide combined with the antioxidant properties of green tea and the soothing qualities of boswellia.
Sodium Hyaluronate: A salt form of hyaluronic acid that hydrates by drawing water into the outer layers from within the skin. It holds up to 1,000 times its weight in water, making skin appear plumper, softer and smoother.
Full Ingredient List: WATER/AQUA/EAU, GLYCERIN, PROPANEDIOL, DIMETHICONE, CAPRYLIC/CAPRIC TRIGLYCERIDE, ISOSTEARYL ALCOHOL, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, NIACINAMIDE, RETINOL, BOSWELLIA SERRATA GUM, CAMELLIA SINENSIS LEAF EXTRACT, ALOE BARBADENSIS LEAF JUICE, CHLORELLA VULGARIS EXTRACT, TETRAPEPTIDE-14, PALMITOYL TRIPEPTIDE-38, HYDROXYPROPYL CYCLODEXTRIN, SODIUM HYALURONATE, HYDROLYZED HYALURONIC ACID, LECITHIN, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, GLUCONOLACTONE, POLYSILICONE-11, POLYURETHANE CROSSPOLYMER-1, BUTYLENE GLYCOL, XANTHAN GUM, TOCOPHEROL, SORBITAN ISOSTEARATE, METHYLPROPANEDIOL, POLYVINYL ALCOHOL, CAPRYLYL GLYCOL, CALCIUM GLUCONATE, HYDROXYACETOPHENONE, DECYL GLUCOSIDE, PHENYLPROPANOL, LACTIC ACID, CITRIC ACID, DISODIUM EDTA, SODIUM HYDROXIDE, SODIUM BENZOATE, 1,2-HEXANEDIOL.
Backed by Science
At 1.0% concentration, retinol drives a significantly accelerated rate of visible skin renewal, addressing the most advanced skin concerns, from deep structural changes in the appearance of skin to significant tone irregularities and acne presentation. The clinical challenge at this concentration is not efficacy; it is maintaining the barrier integrity and skin comfort needed to sustain consistent use, which is what ultimately determines long-term outcomes.
IntelliRET™ 1.0+ applies the full IntelliRET™ system to this challenge. Microencapsulation controls the delivery rate of retinol at maximum concentration, attenuating the irritation peak without attenuating visible efficacy. The bio-inspired botanical booster (Chlorella vulgaris) provides a synergistic enhancement to visible renewal outcomes while simultaneously supporting a more balanced skin response, allowing skin to better adapt to and consistently tolerate the 1.0% concentration over time.
Niacinamide provides active barrier reinforcement throughout, while the Matrixyl® Synthe'6™ peptide and calming complex address the skin comfort and structural support requirements of sustained high-strength retinol use.
The result is a maximum-strength retinol formula that operates at the highest level of corrective performance achievable in a cosmetic retinol serum, supported by a system designed to make that performance sustainable, consistent, and clinically meaningful over time.
Artificial fragrance free
Dye free
Paraben free
Sulfate free
Phthalate free
Animal cruelty free

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Oxidative Aging™ Defense
Oxidative Aging™ Defense
IntelliRET™ 1.0+ delivers the full power of high-strength retinol renewal, targeting deep fine lines, loss of firmness, hyperpigmentation and acne-prone skin, through a system that supports the barrier integrity and skin comfort needed to maintain it. Designed for progression, it should be used under professional guidance.
Retinol, but not as you know it.
Retinol. Reengineered.
Retinol. Reengineered.
IntelliRET™ is a core pillar of the AlumierMD CORE 4 Essentials, a clinically grounded retinol system built for the realities of modern skin. Every IntelliRET™ formula is developed by a global team of scientists and medical professionals with over 100 years of combined industry experience, validated through independent clinical trials, and available exclusively through AlumierMD-authorized clinics and professionals in 12+ countries. Speak to your AlumierMD professional to find out which IntelliRET™ strength is right for your skin.
What is the best hydroquinone-free serum for hyperpigmentation?
AlumierMD’s approach to hyperpigmentation is built around high-efficacy alternatives to hydroquinone. Our formulations combine therapeutic-level actives including L-Ascorbic Acid USP, Kojic Acid, Licorice Root, and Emblica™ to target melanin synthesis across multiple stages of the pathway. The result is clinically visible brightening without the regulatory restrictions and long-term risks associated with hydroquinone, making our serums a medical-grade solution for all skin tones.
How does L-Ascorbic Acid help with dark spots and sun damage?
L-Ascorbic Acid is the most clinically substantiated brightening antioxidant available. At therapeutic concentrations, it inhibits tyrosinase, the key enzyme in melanin production, while simultaneously neutralising the free radicals generated by UV exposure, the primary environmental driver of new pigment formation. AlumierMD’s EverActive C&E® + Peptide delivers 15% L-Ascorbic Acid USP in a stabilized encapsulated format, ensuring this potent ingredient remains active and bioavailable at the point of use.
How does oxidative stress contribute to dark spots, and how do AlumierMD serums help?
UV exposure, pollution, and infrared radiation generate free radicals that can disrupt the skin’s natural homogeneity and stimulate melanin production, worsening the appearance of existing pigmentation and triggering new dark spots over time. AlumierMD serums provide multi-layered antioxidant protection to neutralize this oxidative burden, helping to slow the formation of new pigment irregularity. Paired with a daily AlumierMD broad-spectrum mineral sunscreen, our brightening serums form a complete defense and correction strategy.
Can brightening serums be used alongside retinol?
Yes, and for many skin types this combination produces superior results. Retinol accelerates cellular turnover, helping to lift hyperpigmentation to the surface, while brightening actives continue to suppress further melanin production. AlumierMD offers a tiered retinol range (0.25 to 1.0) to ensure safe, gradual introduction alongside your brightening serums. Professional guidance is recommended to determine the optimal layering sequence and frequency.
How do I order AlumierMD products?
To order AlumierMD products, you must link your account to one of our certified clinics during the checkout process but a prior consultation with a professional is not required to complete your purchase.
However, to achieve the best results, we highly recommend a consultation with one of our skincare professionals. They will assess your skin and prescribe a customized regimen with the optimal formulations for your specific concerns. For initial guidance, you can also take our skincare quiz for product suggestions.